The next generation technology
The increasing use of mRNA-based applications, both in vials for a speed time to market or in pre-fillable syringes (PFS) for dosing accuracy, poses some technical considerations and challenges during the supply chain and cold storage or during life cycle management.
mRNA solutions being highly sensitive might require low temperature storage. A PFS system is composed of multiple components and the cold storage will stress the overall system potentially compromising some of the components.
At Stevanato Group, thanks to our Analytical Services team, we investigated the suitability of our containers at freezing conditions focusing on Container Closure Integrity (CCI), functionality and mechanical performance to address the needs of the current and future applications to be at the forefront in supporting the market.
Our EZ-fill® ITC syringes passed all the tests of the main challenges we investigated. Check below the results.
Why look at PFS for delivering mRNA-based treatments?
1. Lower vaccine wastage
3. Fill & finish capacity
4. Reduce number of steps in injection
5. Dose accuracy independent of preparation
6. Lower risk of injury/cross-contamination
2. Lower overfill/dead volume